Tips & Tricks GPC/ SEC: What Are the Differences Between GPC, SEC
![Tips & Tricks GPC/ SEC: What Are the Differences Between GPC, SEC](https://cdn.sanity.io/images/0vv8moc6/chroma/a3913c8a2522cf8be230f42ca603ba3658b9c92e-809x459.png?fit=crop&auto=format)
Molar mass distributions, molar mass averages, and polydispersity can be determined by gel permeation chromatography (GPC), size-exclusion chromatography (SEC), and gel filtration chromatography (GFC). This makes this technique indispensable for all scientists in quality control (QC) and R&D who have to work with large molecules. However, the technical terms used can be quite confusing for beginners. This instalment of Tips & Tricks explains more.
![](https://www.researchgate.net/publication/236969818/figure/fig9/AS:299532542857225@1448425531652/Influence-of-the-baseline-limits-on-the-molar-mass-distribution-and-the-molar-mass.png)
10 Influence of the baseline limits on the molar mass distribution
![](https://www.agilent.com/cs/publishingimages/portfolio-infinitylab-gpc-960x540-agilent.jpg)
GPC/SEC Solutions for Macromolecular Characterization
![](https://cdn.sanity.io/images/0vv8moc6/chroma/02935be29441b50883a58eb8a4319a3663bf2d53-600x435.jpg)
Tips & Tricks: GPC/SEC Copolymer Analysis in GPC/SEC 2: Polymer
![](https://www.campoly.com/files/7615/0229/8929/GelPC.png)
Cambridge Polymer Group :: GPC/SEC
![](https://www.degruyter.com/document/doi/10.1515/cti-2020-0024/asset/graphic/j_cti-2020-0024_fig_006.jpg)
Size-exclusion chromatography as a useful tool for the assessment
![](https://www.researchgate.net/profile/Peter-Kilz/publication/346955504/figure/fig1/AS:974407178674177@1609328183125/shows-a-molar-mass-distribution-of-a-PEG-with-a-result-table-displaying-typical-GPC-SEC_Q320.jpg)
PDF) Automated Result Uncertainty Determination in GPC/SEC for
Tips & Tricks GPC/SEC: Separation Range and Resolution. - Document
Tips & Tricks GPC/SEC: Separation Range and Resolution. - Document
![](https://www.agilent.com/cs/publishingimages/ebook-gpc-960x540-agilent_v2.jpg)
GPC/SEC Solutions for Macromolecular Characterization
![](https://www.materials-talks.com/wp-content/uploads/2023/02/Extract-data-custom-figures-SQUARE-02.png)
Gel Permeation Chromatography (GPC) - Materials Talks